Gene: PGR

Alternate names for this Gene: NR3C3|PR

Gene Summary: This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap.

Gene is located in Chromosome: 11

Location in Chromosome : 11q22.1

Description of this Gene: progesterone receptor

Type of Gene: protein-coding