Gene: PIAS1
Alternate names for this Gene: DDXBP1|GBP|GU/RH-II|ZMIZ3
Gene Summary: This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. This protein plays a central role as a transcriptional coregulator of numerous cellular pathways includign the STAT1 and nuclear factor kappaB pathways. Alternate splicing results in multiple transcript variants.
Gene is located in Chromosome: 15
Location in Chromosome : 15q23
Description of this Gene: protein inhibitor of activated STAT 1
Type of Gene: protein-coding