Gene: PIK3CD-AS1

Alternate names for this Gene: C1orf200

Gene Summary:

Gene is located in Chromosome: 1

Location in Chromosome : 1p36.22

Description of this Gene: PIK3CD antisense RNA 1

Type of Gene: ncRNA

Gene: PIK3CD

Alternate names for this Gene: APDS|IMD14|P110DELTA|PI3K|p110D

Gene Summary: Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I PI3K found primarily in leukocytes. Like other class I PI3Ks (p110-alpha p110-beta, and p110-gamma), the encoded protein binds p85 adapter proteins and GTP-bound RAS. However, unlike the other class I PI3Ks, this protein phosphorylates itself, not p85 protein.

Gene is located in Chromosome: 1

Location in Chromosome : 1p36.22

Description of this Gene: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta

Type of Gene: protein-coding

rs4240895 in PIK3CD-AS1;PIK3CD gene and Testicular Germ Cell Tumor PMID 28604728 2017 Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor.

rs4240896 in PIK3CD-AS1;PIK3CD gene and White Blood Cell Count procedure PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.