Gene: PKDCC
Alternate names for this Gene: RLSDF|SGK493|Vlk
Gene Summary:
Gene is located in Chromosome: 2
Location in Chromosome : 2p21
Description of this Gene: protein kinase domain containing, cytoplasmic
Type of Gene: protein-coding
rs78572108 in
PKDCC gene and
Bone Density
PMID 29304378 2018 Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects.
rs761532715 in
PKDCC gene and
Dysmorphic features
PMID 23792766 2013 The hedgehog target Vlk genetically interacts with Gli3 to regulate chondrocyte differentiation during mouse long bone development.
PMID 19097194 2009 Short limbs, cleft palate, and delayed formation of flat proliferative chondrocytes in mice with targeted disruption of a putative protein kinase gene, Pkdcc (AW548124).
PMID 23559552 2013 A morpholino-based screen to identify novel genes involved in craniofacial morphogenesis.
PMID 19465597 2009 The novel protein kinase Vlk is essential for stromal function of mesenchymal cells.
PMID 25171405 2014 A secreted tyrosine kinase acts in the extracellular environment.
rs761532715 in
PKDCC gene and
Multiple congenital anomalies
PMID 23559552 2013 A morpholino-based screen to identify novel genes involved in craniofacial morphogenesis.
PMID 23792766 2013 The hedgehog target Vlk genetically interacts with Gli3 to regulate chondrocyte differentiation during mouse long bone development.
PMID 19097194 2009 Short limbs, cleft palate, and delayed formation of flat proliferative chondrocytes in mice with targeted disruption of a putative protein kinase gene, Pkdcc (AW548124).
PMID 19465597 2009 The novel protein kinase Vlk is essential for stromal function of mesenchymal cells.
PMID 25171405 2014 A secreted tyrosine kinase acts in the extracellular environment.
rs763243200 in
PKDCC gene and
Muscle hypotonia
PMID 19097194 2009 Short limbs, cleft palate, and delayed formation of flat proliferative chondrocytes in mice with targeted disruption of a putative protein kinase gene, Pkdcc (AW548124).
PMID 23559552 2013 A morpholino-based screen to identify novel genes involved in craniofacial morphogenesis.
PMID 23792766 2013 The hedgehog target Vlk genetically interacts with Gli3 to regulate chondrocyte differentiation during mouse long bone development.
PMID 25171405 2014 A secreted tyrosine kinase acts in the extracellular environment.
PMID 19465597 2009 The novel protein kinase Vlk is essential for stromal function of mesenchymal cells.
rs761532715 in
PKDCC gene and
Overgrowth
PMID 19097194 2009 Short limbs, cleft palate, and delayed formation of flat proliferative chondrocytes in mice with targeted disruption of a putative protein kinase gene, Pkdcc (AW548124).
PMID 23559552 2013 A morpholino-based screen to identify novel genes involved in craniofacial morphogenesis.
PMID 25171405 2014 A secreted tyrosine kinase acts in the extracellular environment.
PMID 19465597 2009 The novel protein kinase Vlk is essential for stromal function of mesenchymal cells.
PMID 23792766 2013 The hedgehog target Vlk genetically interacts with Gli3 to regulate chondrocyte differentiation during mouse long bone development.