Gene: PLPPR4

Alternate names for this Gene: LPPR4|LPR4|PHP1|PRG-1|PRG1

Gene Summary: The protein encoded by this gene belongs to the lipid phosphate phosphatase (LPP) family. LPPs catalyze the dephosphorylation of a number of bioactive lipid mediators that regulate a variety of cell functions. This protein is specifically expressed in neurons. It is located in the membranes of outgrowing axons and has been shown to be important for axonal outgrowth during development and regenerative sprouting. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene is located in Chromosome: 1

Location in Chromosome : 1p21.3-p21.2

Description of this Gene: phospholipid phosphatase related 4

Type of Gene: protein-coding

rs819913 in PLPPR4 gene and Endometrial Carcinoma PMID 30093612 2018 Identification of nine new susceptibility loci for endometrial cancer.