Gene: PMF1

Alternate names for this Gene: -

Gene Summary:

Gene is located in Chromosome: 1

Location in Chromosome : 1q22

Description of this Gene: polyamine modulated factor 1

Type of Gene: protein-coding

Gene: PMF1-BGLAP

Alternate names for this Gene: PMF-1|PMF1

Gene Summary: This locus represents naturally occurring read-through transcription between the neighboring PMF1 (polyamine-modulated factor 1) and BGLAP (bone gamma-carboxyglutamate Gla protein) genes on chromosome 1. Alternative splicing results in multiple transcript variants encoding isoforms that share sequence identity with the upstream gene product, but they contain distinct C-termini due to frameshifts versus the downstream gene coding sequence.

Gene is located in Chromosome: 1

Location in Chromosome : 1q22

Description of this Gene: PMF1-BGLAP readthrough

Type of Gene: protein-coding

rs1052053 in PMF1;PMF1-BGLAP gene and Cerebral Hemorrhage PMID 24656865 2014 Meta-analysis of genome-wide association studies identifies 1q22 as a susceptibility locus for intracerebral hemorrhage.

rs1052053 in PMF1;PMF1-BGLAP gene and Cerebrovascular accident PMID 29531354 2018 Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.

rs2842870 in PMF1;PMF1-BGLAP gene and Glomerular Filtration Rate PMID 30604766 2019 Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies.

rs1052053 in PMF1;PMF1-BGLAP gene and Ischemic stroke PMID 29531354 2018 Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.