Gene: PNMT

Alternate names for this Gene: PENT|PNMTase

Gene Summary: The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production. Alternatively spliced transcript variants have been found for this gene.

Gene is located in Chromosome: 17

Location in Chromosome : 17q12

Description of this Gene: phenylethanolamine N-methyltransferase

Type of Gene: protein-coding

rs876493 in PNMT gene and Pancreatic carcinoma PMID 30541042 2019 Agnostic Pathway/Gene Set Analysis of Genome-Wide Association Data Identifies Associations for Pancreatic Cancer.