Gene: POLG2

Alternate names for this Gene: HP55|MTDPS16|MTPOLB|PEOA4|POLB|POLG-BETA|POLGB

Gene Summary: This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.

Gene is located in Chromosome: 17

Location in Chromosome : 17q23.3

Description of this Gene: DNA polymerase gamma 2, accessory subunit

Type of Gene: protein-coding

rs9905016 in POLG2 gene and Height PMID 22021425 2012 Genome-wide association study of body height in African Americans: the Women's Health Initiative SNP Health Association Resource (SHARe).