Gene: POLR2L

Alternate names for this Gene: RBP10|RPABC5|RPB10|RPB10beta|RPB7.6|hRPB7.6

Gene Summary: This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains four conserved cysteines characteristic of an atypical zinc-binding domain. Like its counterpart in yeast, this subunit may be shared by the other two DNA-directed RNA polymerases.

Gene is located in Chromosome: 11

Location in Chromosome : 11p15.5

Description of this Gene: RNA polymerase II, I and III subunit L

Type of Gene: protein-coding

Gene: CD151

Alternate names for this Gene: GP27|MER2|PETA-3|RAPH|SFA1|TSPAN24

Gene Summary: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene.

Gene is located in Chromosome: 11

Location in Chromosome : 11p15.5

Description of this Gene: CD151 molecule (Raph blood group)

Type of Gene: protein-coding