Gene: POM121

Alternate names for this Gene: P145|POM121A

Gene Summary: This gene encodes a transmembrane protein that localizes to the inner nuclear membrane and forms a core component of the nuclear pore complex, which mediates transport to and from the nucleus. The encoded protein may anchor this complex to the nuclear envelope. There are multiple related genes and pseudogenes for this gene on chromosomes 5, 7, 15, and 22. Alternatively spliced transcript variants encoding different isoforms have been observed.

Gene is located in Chromosome: 7

Location in Chromosome : 7q11.23

Description of this Gene: POM121 transmembrane nucleoporin

Type of Gene: protein-coding

rs141884613 in POM121 gene and Body mass index PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs7782791 in POM121 gene and Intelligence PMID 29844566 2018 Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.