Gene: POU5F1B

Alternate names for this Gene: OCT4-PG1|OCT4PG1|OTF3C|OTF3P1|POU5F1P1|POU5F1P4|POU5FLC20|POU5FLC8

Gene Summary: This intronless gene was thought to be a transcribed pseudogene of POU class 5 homeobox 1, however, it has been reported that this gene can encode a functional protein. The encoded protein is nearly the same length as and highly similar to the POU class 5 homeobox 1 transcription factor, has been shown to be a weak transcriptional activator and may play a role in carcinogenesis and eye development.

Gene is located in Chromosome: 8

Location in Chromosome : 8q24.21

Description of this Gene: POU class 5 homeobox 1B

Type of Gene: protein-coding

Gene: PCAT1

Alternate names for this Gene: PCA1|PCAT-1|PiHL

Gene Summary: This gene produces a long non-coding RNA that promotes cell proliferation and is upregulated in prostate, colorectal, and other cancers. This RNA negatively regulates the BRCA2 tumor suppressor protein and positively regulates Myc oncoprotein. It contains binding sites for microRNAs, and may act as a sponge for microRNAs that regulate cell growth pathways.

Gene is located in Chromosome: 8

Location in Chromosome : 8q24.21

Description of this Gene: prostate cancer associated transcript 1

Type of Gene: ncRNA

Gene: CCAT2

Alternate names for this Gene: LINC00873|NCCP1

Gene Summary: This gene produces a long non-coding RNA that is upregulated in colon cancer and other cancers. This transcript promotes cell proliferation and suppresses apoptosis. It negatively regulates the biogenesis of microRNA 145.

Gene is located in Chromosome: 8

Location in Chromosome : 8q24.21

Description of this Gene: colon cancer associated transcript 2

Type of Gene: ncRNA

Gene: CASC8

Alternate names for this Gene: CARLO1|CARLo-1|LINC00860

Gene Summary:

Gene is located in Chromosome: 8

Location in Chromosome : 8q24.21

Description of this Gene: cancer susceptibility 8

Type of Gene: ncRNA

rs12682374 in POU5F1B;PCAT1;CCAT2;CASC8 gene and Adenocarcinoma of large intestine PMID 29471430 2018 GWAS identifies two novel colorectal cancer loci at 16q24.1 and 20q13.12.

rs12682374 in POU5F1B;PCAT1;CCAT2;CASC8 gene and COLORECTAL CANCER, SUSCEPTIBILITY TO, 1 PMID 29471430 2018 GWAS identifies two novel colorectal cancer loci at 16q24.1 and 20q13.12.

rs12682374 in POU5F1B;PCAT1;CCAT2;CASC8 gene and COLORECTAL CANCER, SUSCEPTIBILITY TO, 10 PMID 29471430 2018 GWAS identifies two novel colorectal cancer loci at 16q24.1 and 20q13.12.

rs12682374 in POU5F1B;PCAT1;CCAT2;CASC8 gene and COLORECTAL CANCER, SUSCEPTIBILITY TO, 12 PMID 29471430 2018 GWAS identifies two novel colorectal cancer loci at 16q24.1 and 20q13.12.

rs12682374 in POU5F1B;PCAT1;CCAT2;CASC8 gene and COLORECTAL CANCER, SUSCEPTIBILITY TO, 3 PMID 29471430 2018 GWAS identifies two novel colorectal cancer loci at 16q24.1 and 20q13.12.

rs12682374 in POU5F1B;PCAT1;CCAT2;CASC8 gene and Colorectal Carcinoma PMID 29471430 2018 GWAS identifies two novel colorectal cancer loci at 16q24.1 and 20q13.12.

rs12682374 in POU5F1B;PCAT1;CCAT2;CASC8 gene and Colorectal Neoplasms PMID 29471430 2018 GWAS identifies two novel colorectal cancer loci at 16q24.1 and 20q13.12.

rs12682374 in POU5F1B;PCAT1;CCAT2;CASC8 gene and Malignant neoplasm of large intestine PMID 29471430 2018 GWAS identifies two novel colorectal cancer loci at 16q24.1 and 20q13.12.

rs12682374 in POU5F1B;PCAT1;CCAT2;CASC8 gene and Malignant tumor of colon PMID 29471430 2018 GWAS identifies two novel colorectal cancer loci at 16q24.1 and 20q13.12.