Gene: PPIE

Alternate names for this Gene: CYP-33|CYP33

Gene Summary: The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein contains a highly conserved cyclophilin (CYP) domain as well as an RNA-binding domain. It was shown to possess PPIase and protein folding activities, and it also exhibits RNA-binding activity. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 1, has been identified.

Gene is located in Chromosome: 1

Location in Chromosome : 1p34.2

Description of this Gene: peptidylprolyl isomerase E

Type of Gene: protein-coding