Gene: PPIEL
Alternate names for this Gene: PPIEP1
Gene Summary: This transcribed pseudogene is related to PPIE (Gene ID: 10450). Expression of this pseudogene may be downregulated in non-small cell lung cancer (NSCLC). Differential DNA methylation of this locus may be associated with intellectual disability and bipolar disorder in human patients.
Gene is located in Chromosome: 1
Location in Chromosome : 1p34.3
Description of this Gene: peptidylprolyl isomerase E like pseudogene
Type of Gene: pseudo
Gene: BMP8A
Alternate names for this Gene: OP-2
Gene Summary: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein may play a role in development of the reproductive system. This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1.
Gene is located in Chromosome: 1
Location in Chromosome : 1p34.3
Description of this Gene: bone morphogenetic protein 8a
Type of Gene: protein-coding