Gene: PPIF

Alternate names for this Gene: CYP3|CyP-M|Cyp-D|CypD

Gene Summary: The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death.

Gene is located in Chromosome: 10

Location in Chromosome : 10q22.3

Description of this Gene: peptidylprolyl isomerase F

Type of Gene: protein-coding

rs7332 in PPIF gene and Reticulocyte count (procedure) PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.