Gene: PPP1R11

Alternate names for this Gene: CFAP255|HCG-V|HCGV|IPP3|TCTE5|TCTEX5

Gene Summary: This gene encodes a specific inhibitor of protein phosphatase-1 (PP1) with a differential sensitivity toward the metal-independent and metal-dependent forms of PP1. The gene is located within the major histocompatibility complex class I region on chromosome 6.

Gene is located in Chromosome: 6

Location in Chromosome : 6p22.1

Description of this Gene: protein phosphatase 1 regulatory inhibitor subunit 11

Type of Gene: protein-coding

rs3807031 in PPP1R11 gene and Rheumatoid Arthritis PMID 17804836 2007 TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study.

PMID 19503088 2009 REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis.