Gene: PPP1R16A

Alternate names for this Gene: MYPT3

Gene Summary: Myosin light chain kinase and phosphatase (MLCP) complexes control the phosphorylation states of regulatory myosin light chains, which is crucial for muscle and intracellular movement. MLCPs typically contain a catalytic protein phosphatase 1 (PP1c) subunit, a myosin phosphatase targeting (MYPT) subunit, and another smaller subunit. The protein encoded by this gene represents an MYPT subunit, which is responsible for directing PP1c to its intended targets. However, while the phosphorylation of other MYPT members results in PP1c inactivation, phosphorylation of the encoded protein by protein kinase A results in PP1c activation.

Gene is located in Chromosome: 8

Location in Chromosome : 8q24.3

Description of this Gene: protein phosphatase 1 regulatory subunit 16A

Type of Gene: protein-coding

Gene: FOXH1

Alternate names for this Gene: FAST-1|FAST1

Gene Summary: FOXH1 encodes a human homolog of Xenopus forkhead activin signal transducer-1. FOXH1 protein binds SMAD2 and activates an activin response element via binding the DNA motif TGT(G/T)(T/G)ATT.

Gene is located in Chromosome: 8

Location in Chromosome : 8q24.3

Description of this Gene: forkhead box H1

Type of Gene: protein-coding