Gene: PPP1R3A

Alternate names for this Gene: GM|PP1G|PPP1R3

Gene Summary: The glycogen-associated form of protein phosphatase-1 (PP1) derived from skeletal muscle is a heterodimer composed of a 37-kD catalytic subunit and a 124-kD targeting and regulatory subunit. This gene encodes the regulatory subunit which binds to muscle glycogen with high affinity, thereby enhancing dephosphorylation of glycogen-bound substrates for PP1 such as glycogen synthase and glycogen phosphorylase kinase.

Gene is located in Chromosome: 7

Location in Chromosome : 7q31.1

Description of this Gene: protein phosphatase 1 regulatory subunit 3A

Type of Gene: protein-coding

rs12705932 in PPP1R3A gene and Low density lipoprotein cholesterol measurement PMID 31201950 2019 Analysis of pleiotropic genetic effects on cognitive impairment, systemic inflammation, and plasma lipids in the Health and Retirement Study.

rs71571192 in PPP1R3A gene and Serum total cholesterol measurement PMID 31201950 2019 Analysis of pleiotropic genetic effects on cognitive impairment, systemic inflammation, and plasma lipids in the Health and Retirement Study.