Gene: PPP2R3C

Alternate names for this Gene: C14orf10|G4-1|G5pr|GDRM|SPGF36

Gene Summary: This gene encodes a regulatory subunit of the serine/threonine phosphatase, protein phosphatase 2. This protein is localized to both nuclear and cytoplasmic regions depending on cell cycle phase. Homozygous conditional knockout mice for this gene exhibit reduced numbers and impaired proliferation of immune system B cells. This protein may regulate the expression of the P-glycoprotein ATP-binding cassette transporter through its phosphatase activity. Alternative splicing results in multiple transcript variants.

Gene is located in Chromosome: 14

Location in Chromosome : 14q13.2

Description of this Gene: protein phosphatase 2 regulatory subunit B''gamma

Type of Gene: protein-coding

rs72664829 in PPP2R3C gene and White Blood Cell Count procedure PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.