Gene: PPT2-EGFL8

Alternate names for this Gene: PPT-2|PPT2

Gene Summary: This locus represents naturally occurring read-through transcription between the neighboring PPT2 (palmitoyl-protein thioesterase 2) and EGFL8 (EGF-like-domain, multiple 8) genes located in the major histocompatibility complex class III region of chromosome 6. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is thus unlikely to produce a protein product.

Gene is located in Chromosome: 6

Location in Chromosome : 6p21.32

Description of this Gene: PPT2-EGFL8 readthrough (NMD candidate)

Type of Gene: ncRNA

Gene: LOC100507547

Alternate names for this Gene: -

Gene Summary:

Gene is located in Chromosome: 6

Location in Chromosome : 6p21.32

Description of this Gene: uncharacterized LOC100507547

Type of Gene: ncRNA

Gene: PRRT1

Alternate names for this Gene: C6orf31|DSPD1|IFITMD7|NG5

Gene Summary:

Gene is located in Chromosome: 6

Location in Chromosome : 6p21.32

Description of this Gene: proline rich transmembrane protein 1

Type of Gene: protein-coding

Gene: PPT2

Alternate names for this Gene: C6orf8|G14|PPT-2

Gene Summary: This gene encodes a member of the palmitoyl-protein thioesterase family. The encoded glycosylated lysosomal protein has palmitoyl-CoA hydrolase activity in vitro, but does not hydrolyze palmitate from cysteine residues in proteins. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream EGFL8 (EGF-like-domain, multiple 8) gene.

Gene is located in Chromosome: 6

Location in Chromosome : 6p21.32

Description of this Gene: palmitoyl-protein thioesterase 2

Type of Gene: protein-coding

rs1053924 in PPT2-EGFL8;LOC100507547;PRRT1;PPT2 gene and Diabetes Mellitus, Insulin-Dependent PMID 17632545 2007 A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene.