Gene: PRH1-PRR4

Alternate names for this Gene: PRH1

Gene Summary: This locus represents naturally occurring read-through transcription between the neighboring PRH1 (proline-rich protein HaeIII subfamily 1) and PRR4 (proline rich 4, lacrimal) genes on chromosome 12. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is thus unlikely to produce a protein product.

Gene is located in Chromosome: 12

Location in Chromosome : 12p13.2

Description of this Gene: PRH1-PRR4 readthrough

Type of Gene: ncRNA

Gene: PRH1-TAS2R14

Alternate names for this Gene: -

Gene Summary: This locus represents naturally occurring readthrough transcription between the neighboring PRH1 (proline-rich protein HaeIII subfamily 1) and TAS2R14 (taste receptor, type 2, member 14) genes on chromosome 12. The readthrough transcript encodes a fusion protein that shares sequence identity with each individual gene product.

Gene is located in Chromosome: 12

Location in Chromosome : 12p13.2

Description of this Gene: PRH1-TAS2R14 readthrough

Type of Gene: protein-coding

Gene: PRR4

Alternate names for this Gene: LPRP|PROL4

Gene Summary: This gene encodes a member of the proline-rich protein family that lacks a conserved repetitive domain. This protein may play a role in protective functions in the eye. Alternative splicing result in multiple transcript variants. Read-through transcription also exists between this gene and the upstream PRH1 (proline-rich protein HaeIII subfamily 1) gene.

Gene is located in Chromosome: 12

Location in Chromosome : 12p13.2

Description of this Gene: proline rich 4

Type of Gene: protein-coding

Gene: PRH1

Alternate names for this Gene: Db-s|PA|PIF-S|PRH2|Pr1/Pr2

Gene Summary: This gene encodes a member of the heterogeneous family of proline-rich salivary glycoproteins. The encoded preproprotein undergoes proteolytic processing to generate one or more mature isoforms before secretion from the parotid and submandibular/sublingual glands. Multiple distinct alleles of this locus including the parotid isoelectric-focusing variant slow (PIF-s), the parotid acidic protein (Pa), and the double band slow (Db-s) isoforms have been characterized. The reference genome encodes the Db-s allele. Certain alleles of this gene are associated with susceptibility to dental caries. This gene is located in a cluster of closely related salivary proline-rich proteins on chromosome 12. Co-transcription of this gene with adjacent genes has been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.

Gene is located in Chromosome: 12

Location in Chromosome : 12p13.2

Description of this Gene: proline rich protein HaeIII subfamily 1

Type of Gene: protein-coding

Gene: TAS2R14

Alternate names for this Gene: T2R14|TRB1

Gene Summary: This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13.

Gene is located in Chromosome: 12

Location in Chromosome : 12p13.2

Description of this Gene: taste 2 receptor member 14

Type of Gene: protein-coding