Gene: PRKCQ-AS1

Alternate names for this Gene: -

Gene Summary:

Gene is located in Chromosome: 10

Location in Chromosome : 10p15.1

Description of this Gene: PRKCQ antisense RNA 1

Type of Gene: ncRNA

Gene: PRKCQ

Alternate names for this Gene: PRKCT|nPKC-theta

Gene Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors.

Gene is located in Chromosome: 10

Location in Chromosome : 10p15.1

Description of this Gene: protein kinase C theta

Type of Gene: protein-coding

rs943451 in PRKCQ-AS1;PRKCQ gene and Asthma PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs943451 in PRKCQ-AS1;PRKCQ gene and Childhood asthma PMID 31036433 2019 Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies.

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.