Gene: PRKX

Alternate names for this Gene: PKX1

Gene Summary: This gene encodes a serine threonine protein kinase that has similarity to the catalytic subunit of cyclic AMP dependent protein kinases. The encoded protein is developmentally regulated and may be involved in renal epithelial morphogenesis. This protein may also be involved in macrophage and granulocyte maturation. Abnormal recombination between this gene and a related pseudogene on chromosome Y is a frequent cause of sex reversal disorder in XX males and XY females. Pseudogenes of this gene are found on chromosomes X, 15 and Y.

Gene is located in Chromosome: X

Location in Chromosome : Xp22.33

Description of this Gene: protein kinase X-linked

Type of Gene: protein-coding

rs12390237 in PRKX gene and Thyroid stimulating hormone measurement PMID 30367059 2018 Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation.