Gene: PSMD5

Alternate names for this Gene: S5B

Gene Summary: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a non-ATPase subunit of the 19S regulator base that functions as a chaperone protein during 26S proteasome assembly.

Gene is located in Chromosome: 9

Location in Chromosome : 9q33.2

Description of this Gene: proteasome 26S subunit, non-ATPase 5

Type of Gene: protein-coding

Gene: CUTALP

Alternate names for this Gene: PSMD5-AS1

Gene Summary:

Gene is located in Chromosome: 9

Location in Chromosome : 9q33.2

Description of this Gene: cutA divalent cation tolerance like, pseudogene

Type of Gene: pseudo

rs13299616 in PSMD5;CUTALP gene and AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 1 PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs13299616 in PSMD5;CUTALP gene and AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 2 PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs13299616 in PSMD5;CUTALP gene and AUTOIMMUNE DISEASE, SUSCEPTIBILITY TO, 6 PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs13299616 in PSMD5;CUTALP gene and Autoimmune Diseases PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.