Gene: PTBP2

Alternate names for this Gene: PTBLP|brPTB|nPTB

Gene Summary: The protein encoded by this gene binds to intronic polypyrimidine clusters in pre-mRNA molecules and is implicated in controlling the assembly of other splicing-regulatory proteins. This protein is very similar to the polypyrimidine tract binding protein (PTB) but most of its isoforms are expressed primarily in the brain. Alternative splicing results in multiple transcript variants.

Gene is located in Chromosome: 1

Location in Chromosome : 1p21.3

Description of this Gene: polypyrimidine tract binding protein 2

Type of Gene: protein-coding

rs3748784 in PTBP2 gene and Headache PMID 29397368 2018 A Genome-Wide Association Study Finds Genetic Associations with Broadly-Defined Headache in UK Biobank (N=223,773).