Gene: PTGES3

Alternate names for this Gene: P23|TEBP|cPGES

Gene Summary: This gene encodes an enzyme that converts prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). This protein functions as a co-chaperone with heat shock protein 90 (HSP90), localizing to response elements in DNA and disrupting transcriptional activation complexes. Alternative splicing results in multiple transcript variants. There are multiple pseudogenes of this gene on several different chromosomes.

Gene is located in Chromosome: 12

Location in Chromosome : 12q13.3|12

Description of this Gene: prostaglandin E synthase 3

Type of Gene: protein-coding

rs2290893 in PTGES3 gene and Reticulocyte count (procedure) PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.