Gene: PTGIR
Alternate names for this Gene: IP|PRIPR
Gene Summary: The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor.
Gene is located in Chromosome: 19
Location in Chromosome : 19q13.32
Description of this Gene: prostaglandin I2 receptor
Type of Gene: protein-coding
rs11083840 in
PTGIR gene and
Ulcerative Colitis
PMID 26192919 2015 Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.
PMID 23128233 2012 Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.