Gene: PURB

Alternate names for this Gene: PURBETA

Gene Summary: This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia.

Gene is located in Chromosome: 7

Location in Chromosome : 7p13

Description of this Gene: purine rich element binding protein B

Type of Gene: protein-coding