Gene: PWRN1

Alternate names for this Gene: NCRNA00198

Gene Summary: This gene is located in the Prader-Willi syndrome (PWS) region of chromosome 15, which is known to undergo imprinting. The transcript is believed to be non-coding. It is bi-allelically expressed in testis and kidney, but mono-allelically expressed from the paternal allele in brain. This gene is poly-adenylated and is known to undergo alternative splicing. Transcript variants may represent part of a complex imprinting center-SNURF-SNRPN transcription unit. The contribution of this gene to the PWS phenotype is unknown, but it has been suggested that it may play a role in establishing paternal imprinting in the PWS region, perhaps by maintaining the paternal allele in an open chromatin configuration.

Gene is located in Chromosome: 15

Location in Chromosome : 15q11.2

Description of this Gene: Prader-Willi region non-protein coding RNA 1

Type of Gene: ncRNA

Gene: LOC102723749

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Gene: LOC105370733

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