Gene: PYCARD-AS1

Alternate names for this Gene: C16orf98|PYCARDOS

Gene Summary:

Gene is located in Chromosome: 16

Location in Chromosome : 16p11.2

Description of this Gene: PYCARD antisense RNA 1

Type of Gene: ncRNA

Gene: PYCARD

Alternate names for this Gene: ASC|CARD5|TMS|TMS-1|TMS1

Gene Summary: This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene.

Gene is located in Chromosome: 16

Location in Chromosome : 16p11.2

Description of this Gene: PYD and CARD domain containing

Type of Gene: protein-coding