Gene: RAPH1

Alternate names for this Gene: ALS2CR18|ALS2CR9|LPD|PREL-2|PREL2|RMO1|RalGDS/AF-6

Gene Summary: This gene encodes a protein that belongs to the Mig10/Rap1-interacting adaptor molecule/Lamellipodin family of adapter proteins, which function in cell migration. Members of this family contain pleckstrin-homology domains, Ras-association domains, and proline-rich C-termini. The protein encoded by this gene regulates actin dynamics through interaction with Ena/Vasodilator proteins as well as direct binding to filamentous actin to regulate actin network assembly. Alternative splicing results in multiple transcript variants.

Gene is located in Chromosome: 2

Location in Chromosome : 2q33.2

Description of this Gene: Ras association (RalGDS/AF-6) and pleckstrin homology domains 1

Type of Gene: protein-coding

Gene: ABI2

Alternate names for this Gene: ABI-2|ABI2B|AIP-1|AIP1|AblBP3|SSH3BP2|argBP1|argBPIA|argBPIB

Gene Summary:

Gene is located in Chromosome: 2

Location in Chromosome : 2q33.2

Description of this Gene: abl interactor 2

Type of Gene: protein-coding

rs1376877 in RAPH1;ABI2 gene and Pseudocholinesterase Measurement PMID 21862451 2011 GWAS of butyrylcholinesterase activity identifies four novel loci, independent effects within BCHE and secondary associations with metabolic risk factors.