Gene: RARB

Alternate names for this Gene: HAP|MCOPS12|NR1B2|RARbeta1|RRB2

Gene Summary: This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. Alternate promoter usage and differential splicing result in multiple transcript variants.

Gene is located in Chromosome: 3

Location in Chromosome : 3p24.2

Description of this Gene: retinoic acid receptor beta

Type of Gene: protein-coding

Gene: RNA5SP126

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