Gene: RBBP6

Alternate names for this Gene: MY038|P2P-R|PACT|RBQ-1|SNAMA

Gene Summary: The retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle-dependent phosphorylation regulates the activity of pRB. This gene encodes a protein which binds to underphosphorylated but not phosphorylated pRB. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene.

Gene is located in Chromosome: 16

Location in Chromosome : 16p12.1

Description of this Gene: RB binding protein 6, ubiquitin ligase

Type of Gene: protein-coding

rs7195386 in RBBP6 gene and Body Height PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs7195386 in RBBP6 gene and Body mass index PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

PMID 28892062 2017 Genome-wide association study identifies 112 new loci for body mass index in the Japanese population.