Gene: RBX1

Alternate names for this Gene: BA554C12.1|RNF75|ROC1

Gene Summary: This locus encodes a RING finger-like domain-containing protein. The encoded protein interacts with cullin proteins and likely plays a role in ubiquitination processes necessary for cell cycle progression. This protein may also affect protein turnover. Related pseudogenes exist on chromosomes 2 and 5.

Gene is located in Chromosome: 22

Location in Chromosome : 22q13.2

Description of this Gene: ring-box 1

Type of Gene: protein-coding

rs2413631 in RBX1 gene and Anxiety PMID 29942085 2018 Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.