Gene: RCC2

Alternate names for this Gene: TD-60

Gene Summary: The protein encoded by this gene is a guanine exchange factor that is active on RalA, a small GTPase. The encoded protein and RalA are both essential for proper kinetochore-microtubule function in early mitosis. This protein has been shown to be a biomarker for colorectal cancer.

Gene is located in Chromosome: 1

Location in Chromosome : 1p36.13

Description of this Gene: regulator of chromosome condensation 2

Type of Gene: protein-coding

rs57142672 in RCC2 gene and Basal Cell Cancer PMID 27539887 2016 Genome-wide association study identifies 14 novel risk alleles associated with basal cell carcinoma.

PMID 31174203 2019 Combined analysis of keratinocyte cancers identifies novel genome-wide loci.

rs57142672 in RCC2 gene and Basal Cell Neoplasm PMID 27539887 2016 Genome-wide association study identifies 14 novel risk alleles associated with basal cell carcinoma.

PMID 31174203 2019 Combined analysis of keratinocyte cancers identifies novel genome-wide loci.

rs57142672 in RCC2 gene and Basal cell carcinoma PMID 27539887 2016 Genome-wide association study identifies 14 novel risk alleles associated with basal cell carcinoma.

PMID 31174203 2019 Combined analysis of keratinocyte cancers identifies novel genome-wide loci.