Gene: RCN1

Alternate names for this Gene: HEL-S-84|PIG20|RCAL|RCN

Gene Summary: Reticulocalbin 1 is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. High conservation of amino acid residues outside of these motifs, in comparison to mouse reticulocalbin, is consistent with a possible biochemical function besides that of calcium binding. In human endothelial and prostate cancer cell lines this protein localizes to the plasma membrane.

Gene is located in Chromosome: 11

Location in Chromosome : 11p13

Description of this Gene: reticulocalbin 1

Type of Gene: protein-coding

rs223058 in RCN1 gene and Body mass index PMID 30239722 2019 Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.