Gene: RENBP

Alternate names for this Gene: RBP|RNBP

Gene Summary: The gene product inhibits renin activity by forming a dimer with renin, a complex known as high molecular weight renin. The encoded protein contains a leucine zipper domain, which is essential for its dimerization with renin. The gene product can catalyze the interconversion of N-acetylglucosamine to N-acetylmannosamine, indicating that it is a GlcNAc 2-epimerase. Transcript variants utilizing alternative promoters have been described in the literature.

Gene is located in Chromosome: X

Location in Chromosome : Xq28

Description of this Gene: renin binding protein

Type of Gene: protein-coding

rs2269372 in RENBP gene and Schizophrenia PMID 24043878 2014 Common variants on Xq28 conferring risk of schizophrenia in Han Chinese.