Gene: REPS2
Alternate names for this Gene: POB1
Gene Summary: The product of this gene is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral. Its expression can negatively affect receptor internalization and inhibit growth factor signaling. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene is located in Chromosome: X
Location in Chromosome : Xp22.2
Description of this Gene: RALBP1 associated Eps domain containing 2
Type of Gene: protein-coding
rs143049324 in
REPS2 gene and
Smoking
PMID 26053186 2015 Mercapturic Acids Derived from the Toxicants Acrolein and Crotonaldehyde in the Urine of Cigarette Smokers from Five Ethnic Groups with Differing Risks for Lung Cancer.
rs143049324 in
REPS2 gene and
Smoking Behaviors
PMID 26053186 2015 Mercapturic Acids Derived from the Toxicants Acrolein and Crotonaldehyde in the Urine of Cigarette Smokers from Five Ethnic Groups with Differing Risks for Lung Cancer.