Gene: REV1

Alternate names for this Gene: AIBP80|REV1L

Gene Summary: This gene encodes a protein with similarity to the S. cerevisiae mutagenesis protein Rev1. The Rev1 proteins contain a BRCT domain, which is important in protein-protein interactions. A suggested role for the human Rev1-like protein is as a scaffold that recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA.

Gene is located in Chromosome: 2

Location in Chromosome : 2q11.2

Description of this Gene: REV1 DNA directed polymerase

Type of Gene: protein-coding

rs1011633 in REV1 gene and Major Depressive Disorder PMID 22472876 2013 A mega-analysis of genome-wide association studies for major depressive disorder.

rs3792142 in REV1 gene and mathematical ability PMID 30038396 2018 Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.