Gene: REV3L

Alternate names for this Gene: POLZ|REV3

Gene Summary: The protein encoded by this gene represents the catalytic subunit of DNA polymerase zeta, which functions in translesion DNA synthesis. The encoded protein can be found in mitochondria, where it protects DNA from damage. Defects in this gene are a cause of Mobius syndrome.

Gene is located in Chromosome: 6

Location in Chromosome : 6q21

Description of this Gene: REV3 like, DNA directed polymerase zeta catalytic subunit

Type of Gene: protein-coding

Gene: MFSD4B

Alternate names for this Gene: KIAA1919|NaGLT1|SLC60A2

Gene Summary:

Gene is located in Chromosome: 6

Location in Chromosome : 6q21

Description of this Gene: major facilitator superfamily domain containing 4B

Type of Gene: protein-coding

rs7760535 in REV3L;MFSD4B gene and Glucose measurement PMID 21886157 2011 Human metabolic individuality in biomedical and pharmaceutical research.

rs1061388 in REV3L;MFSD4B gene and Serum albumin measurement PMID 22286219 2012 Genome-wide association study identifies multiple loci influencing human serum metabolite levels.

rs240955 in REV3L;MFSD4B gene and Smoking PMID 30643258 2019 Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.

rs7760535 in REV3L;MFSD4B gene and elevated blood glucose level PMID 21886157 2011 Human metabolic individuality in biomedical and pharmaceutical research.