Gene: REV3L

Alternate names for this Gene: POLZ|REV3

Gene Summary: The protein encoded by this gene represents the catalytic subunit of DNA polymerase zeta, which functions in translesion DNA synthesis. The encoded protein can be found in mitochondria, where it protects DNA from damage. Defects in this gene are a cause of Mobius syndrome.

Gene is located in Chromosome: 6

Location in Chromosome : 6q21

Description of this Gene: REV3 like, DNA directed polymerase zeta catalytic subunit

Type of Gene: protein-coding

rs10872067 in REV3L gene and Serum albumin measurement PMID 22286219 2012 Genome-wide association study identifies multiple loci influencing human serum metabolite levels.