Gene: RGS1

Alternate names for this Gene: 1R20|BL34|HEL-S-87|IER1|IR20

Gene Summary: This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.

Gene is located in Chromosome: 1

Location in Chromosome : 1q31.2

Description of this Gene: regulator of G protein signaling 1

Type of Gene: protein-coding

Gene: LOC105371664

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