Gene: RGS5

Alternate names for this Gene: MST092|MST106|MST129|MSTP032|MSTP092|MSTP106|MSTP129

Gene Summary: This gene encodes a member of the regulators of G protein signaling (RGS) family. The RGS proteins are signal transduction molecules which are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators. This gene is a hypoxia-inducible factor-1 dependent, hypoxia-induced gene which is involved in the induction of endothelial apoptosis. This gene is also one of three genes on chromosome 1q contributing to elevated blood pressure. Alternatively spliced transcript variants have been identified.

Gene is located in Chromosome: 1

Location in Chromosome : 1q23.3

Description of this Gene: regulator of G protein signaling 5

Type of Gene: protein-coding

rs902727464 in RGS5 gene and Periprosthetic osteolysis PMID 30794219 2019 The 2018 Otto Aufranc Award: How Does Genome-wide Variation Affect Osteolysis Risk After THA?