Gene: RHOA
Alternate names for this Gene: ARH12|ARHA|EDFAOB|RHO12|RHOH12
Gene Summary: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified.
Gene is located in Chromosome: 3
Location in Chromosome : 3p21.31
Description of this Gene: ras homolog family member A
Type of Gene: protein-coding
Gene: TCTA
Alternate names for this Gene: -
Gene Summary:
Gene is located in Chromosome: 3
Location in Chromosome : 3p21.31
Description of this Gene: T cell leukemia translocation altered
Type of Gene: protein-coding
rs7623687 in
RHOA;TCTA gene and
Coronary Artery Disease
PMID 29212778 2018 Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.
PMID 28714975 2017 Association analyses based on false discovery rate implicate new loci for coronary artery disease.
PMID 28714974 2017 Genetic analysis in UK Biobank links insulin resistance and transendothelial migration pathways to coronary artery disease.