Gene: RIMS2

Alternate names for this Gene: CRSDS|OBOE|RAB3IP3|RIM2

Gene Summary: The protein encoded by this gene is a presynaptic protein that interacts with RAB3, a protein important for normal neurotransmitter release. The encoded protein can also bind several other synaptic proteins, including UNC-13 homolog B, ELKS/Rab6-interacting/CAST family member 1, and synaptotagmin 1. This protein is involved in synaptic membrane exocytosis. Polymorphisms in this gene have been associated with degenerative lumbar scoliosis.

Gene is located in Chromosome: 8

Location in Chromosome : 8q22.3

Description of this Gene: regulating synaptic membrane exocytosis 2

Type of Gene: protein-coding