Gene: RNASEH2B

Alternate names for this Gene: AGS2|DLEU8

Gene Summary: RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. The protein encoded by this gene is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Aicardi-Goutieres syndrome type 2 (AGS2).

Gene is located in Chromosome: 13

Location in Chromosome : 13q14.3

Description of this Gene: ribonuclease H2 subunit B

Type of Gene: protein-coding

Gene: GUCY1B2

Alternate names for this Gene: GC-SB2

Gene Summary:

Gene is located in Chromosome: 13

Location in Chromosome : 13q14.3

Description of this Gene: guanylate cyclase 1 soluble subunit beta 2 (pseudogene)

Type of Gene: pseudo

rs3790022 in RNASEH2B;GUCY1B2 gene and Rheumatoid Arthritis PMID 24532677 2015 A genome-wide association study of rheumatoid arthritis without antibodies against citrullinated peptides.