Gene: RPP21

Alternate names for this Gene: C6orf135|CAT60

Gene Summary: RPP21 is a protein subunit of nuclear ribonuclease P, which processes the 5-prime leader sequence of precursor tRNAs (Jarrous et al., 2001 [PubMed 11497433]).[supplied by OMIM, Jan 2009].

Gene is located in Chromosome: 6

Location in Chromosome : 6p22.1

Description of this Gene: ribonuclease P/MRP subunit p21

Type of Gene: protein-coding

Gene: TRIM39

Alternate names for this Gene: RNF23|TFP|TRIM39B

Gene Summary: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The function of this protein has not been identified. This gene lies within the major histocompatibility complex class I region on chromosome 6. Alternate splicing results in two transcript variants encoding different isoforms.

Gene is located in Chromosome: 6

Location in Chromosome : 6p22.1

Description of this Gene: tripartite motif containing 39

Type of Gene: protein-coding

Gene: TRIM39-RPP21

Alternate names for this Gene: TRIM39R

Gene Summary: This locus represents naturally occurring read-through transcription between the neighboring TRIM39 (tripartite motif-containing 39) and RPP21 (ribonuclease P/MRP 21kDa subunit) genes on chromosome 6. The read-through transcript encodes a fusion protein that shares sequence identity with each individual gene product.

Gene is located in Chromosome: 6

Location in Chromosome : 6p22.1

Description of this Gene: TRIM39-RPP21 readthrough

Type of Gene: protein-coding

rs3094067 in RPP21;TRIM39;TRIM39-RPP21 gene and Lupus Erythematosus, Cutaneous PMID 25827949 2015 Genome-wide association study identifies new susceptibility loci for cutaneous lupus erythematosus.