Gene: RPTOR

Alternate names for this Gene: KOG1|Mip1

Gene Summary: This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene is located in Chromosome: 17

Location in Chromosome : 17q25.3

Description of this Gene: regulatory associated protein of MTOR complex 1

Type of Gene: protein-coding

Gene: LOC107985021

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