Gene: RSPO3
Alternate names for this Gene: CRISTIN1|PWTSR|THSD2
Gene Summary: This gene belongs to the R-spondin family. The encoded protein plays a role in the regulation of Wnt (wingless-type MMTV integration site family)/beta-catenin and Wnt/planar cell polarity (PCP) signaling pathways, which are involved in development, cell growth and disease pathogenesis. Genome-wide association studies suggest a correlation of this gene with bone mineral density and risk of fracture. This gene may be involved in tumor development.
Gene is located in Chromosome: 6
Location in Chromosome : 6q22.33
Description of this Gene: R-spondin 3
Type of Gene: protein-coding
Gene: LOC112267972
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