Gene: RTF1

Alternate names for this Gene: GTL7|KIAA0252

Gene Summary: This locus may represent a gene involved in regulation of transcription elongation and chromatin remodeling, based on studies of similar proteins in other organisms. The encoded protein may bind single-stranded DNA.

Gene is located in Chromosome: 15

Location in Chromosome : 15q15.1

Description of this Gene: RTF1 homolog, Paf1/RNA polymerase II complex component

Type of Gene: protein-coding

rs111371454 in RTF1 gene and Allergic rhinitis (disorder) PMID 30013184 2018 Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis.

rs117643004 in RTF1 gene and Intelligence PMID 29844566 2018 Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.

rs2777491 in RTF1 gene and Ulcerative Colitis PMID 26192919 2015 Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.