Gene: RXFP1

Alternate names for this Gene: LGR7|RXFPR1

Gene Summary: This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane receptor superfamily. The encoded protein plays a critical role in sperm motility, pregnancy and parturition as a receptor for the protein hormone relaxin. Decreased expression of this gene may play a role in endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene is located in Chromosome: 4

Location in Chromosome : 4q32.1

Description of this Gene: relaxin family peptide receptor 1

Type of Gene: protein-coding

rs936094 in RXFP1 gene and Precursor Cell Lymphoblastic Leukemia Lymphoma PMID 22076464 2012 Identification of germline susceptibility loci in ETV6-RUNX1-rearranged childhood acute lymphoblastic leukemia.